Search on: KYNURENINE 3-MONOOXYGENASE 
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Descriptor English:   Kynurenine 3-Monooxygenase 
Descriptor Spanish:   Quinurenina 3-Monooxigenasa 
Descriptor Portuguese:   Quinurenina 3-Mono-Oxigenase 
Tree Number:   D08.811.682.690.708.557
Definition English:   An NADPH-dependent flavin monooxygenase that plays a key role in the catabolism of TRYPTOPHAN by catalyzing the HYDROXYLATION of KYNURENINE to 3-hydroxykynurenine. It was formerly characterized as EC 1.14.1.2 and EC 1.99.1.5. 
History Note English:   2006(1980); KYNURENINE 1973-1979 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DU diagnostic use DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   50663 
Unique Identifier:   D050601 

Occurrence in VHL:
 

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